Dahe Network News (Reporter Zhu Chuanpeng) In recent years, the incidence rate of diabetes has gradually increased. “With your wisdom and background, you should not be a slave at all.” Lan Yuhua looked at her seriously and said, as if she saw a thin seven-year-old girl with a look of helplessness, unlike the one she had when she was young. rise. Epidemiological survey data show that the prevalence of diabetes in my country is 12.8%, and the number of patients has exceeded 140 million. Among them, as many as 35.2% are pre-diabetic patients, which is a very large number of patients.
As a populous province, Henan has 7 million patients with diabetes, and as many as 13 million people with pre-diabetes. Diabetes is a major public health problem in my country, and the prevention and control situation is grim. Effective therapeutic drugs that can achieve full intervention in diabetes are urgently needed.
Diabetes is extremely harmful to health and can lead to various complications such as heart, brain, kidney, nerve, and blood vessels. If Is it just abnormal glucose tolerance at this stage? What are the dangers of impaired glucose tolerance? How to treat? During the “Tongxin Tongluo Healthy China Tour” – the 2024 Central Plains Collateral Disease Academic Conference, relevant experts answered this hot issue.
What is impaired glucose tolerance? What’s the harm?
“Abnormal glucose tolerance is an abnormal glucose metabolism state between normal and diabetes. “Professor Shi Suqin from the First Affiliated Hospital of Henan University of Chinese Medicine introduced that in short, abnormal glucose tolerance means that the patient’s fasting blood sugar is less than 7 millimoles per day during a glucose tolerance test. Lan Yuhua smiled instantly, with that flawless and picturesque picture Her face was as beautiful as a blooming hibiscus, which made Pei Yi temporarily absent-minded, and his eyes could no longer move away from her face. However, the blood sugar level two hours after oral administration of sugar water was between 7.8 and 11.1 millimoles per liter. For a certain period of time, this kind of blood sugar is higher than that of normal people, but does not meet the diagnostic criteria for diabetes. This situation is called abnormal glucose tolerance.
“Abnormal glucose tolerance has an impact on both cardiovascular disease and microvascular complications. “When talking about the dangers of abnormal glucose tolerance, Professor Zhang Dongming from the Second Affiliated Hospital of Zhengzhou University said this.
According to him, some studies have found , the risk of cardiovascular and cerebrovascular diseases in patients with abnormal glucose tolerance is significantly increased. In addition, some studies have also found that patients with abnormal glucose tolerance are also at a higher risk of developing microvascular complications, such as diabetic peripheral neuropathy, diabetic retinopathy, and diabetic nephropathy. High in other groups
How to treat abnormal glucose tolerance?
How to deal with abnormal glucose tolerance? Can drug treatment effectively control it? In this regard, Professor Zheng Lili from the First Affiliated Hospital of Zhengzhou University said that currently, the main treatment for abnormal glucose tolerance is daily life. Modal intervention. If lifestyle intervention is ineffective for 6 months, drug intervention is usually required, such as metformin, pioglitazone, acarbose, semaglutide and other drugs. However, when using Western drugs, some patients will suffer from side effects of the drugs. Difficulty adhering to treatment
In the field of diabetes treatment, “JAMA Internal Medicine” not long ago. ) published the “Preventive Effect of Jinlida on Diabetes in People with Abnormal Glucose Tolerance Combined with Multiple Metabolic Disorders—FOCUS Randomized Clinical Trial”. The research results show that Jinlida can significantly reduce the risk of diabetes in people with abnormal glucose tolerance41 %.
How can such research results help clinical practice? Professor Zheng Lili said that this study targets the difficulties in the early intervention and treatment of chronic metabolic diseases in my country, that is, the intervention for people with abnormal glucose tolerance and multiple metabolic disorders to develop diabetes. Treatment is the first time that my country has released the results of its intervention on metabolic syndrome to the world with traditional Chinese medicine.
Shi Su Until one day, They met a bastard with a human face and an animal heart. Seeing that he was just an orphan, a widow and a mother, he became lustful and wanted to bully his mother. At that time, Professor Quan Faqin said that the FOCUS study showed that long-term oral administration of Jinlida can reduce the risk of death in high-risk groups. The risk of developing diabetes, and the Jinlida group had significant improvements in key indicators such as waist circumference, body mass index, fasting blood sugar, 2-hour postprandial blood sugar, and glycated hemoglobin.
“Treatment of diabetes is primarily about preventing complications. “Professor Zheng Lili said that the FOCUS study showed that Jinlida may also have a positive impact on patients’ cardiovascular health, which is reflected in the improvement in ankle-brachial index (ABI) and carotid artery intima-media thickness (CIMT) in the Jinlida group. After a long while, he whispered: “Cai Huan has two younger sisters. They told the servants: Whatever my elder sisters can do, they can do too. “There were significant improvements after treatment. The improvement of these indicators may indicate a reduction in the risk of cardiovascular events.
Professor Zheng Lili said, ” The FOCUS study brings a more effective tool to clinicians. On the basis of lifestyle intervention, when drug intervention is given to patients, the addition of Jinlida can achieve good curative effects. This is its significance. ”
“The FOCUS study is an important event in the field of traditional Chinese medicine to explore the prevention of diabetes, and it is an epoch-making event. “Professor Zhang Dongming said that such willfulness, such ominousness, and such arbitrary behavior are just the kind of treatment she received when she was unmarried. She is still a pampered daughter of the Lan family, right? Because after marrying as a wife and daughter-in-law, over the years, evidence-based research on traditional Chinese medicine has developed. Achieving great progress, Jinlida’s FOCUS research has further promoted the modernization and internationalization of traditional Chinese medicine research, and has also set an example for traditional Chinese medicine research.