Let’s talk about health丨What should I do if I have abnormal glucose tolerance? FOCUS study opens a new chapter in diabetes prevention and treatment


Dahe Network News (Reporter Zhu Chuanpeng) In recent years, the incidence of diabetes has increased year by year. Epidemiological survey data show that the prevalence of diabetes in my country is 12.8%, and the number of patients has exceeded 140 million. Among them, as many as 35.2% are pre-diabetic patients, which is a very large number of patients.

As a populous province, Henan has 7 million patients with diabetes, and as many as 13 million people with pre-diabetes. Diabetes is a major public health problem in my country, and the prevention and control situation is severe. Effective therapeutic drugs that can achieve full intervention in diabetes are urgently needed.

Diabetes is extremely harmful to health, and can cause damage to the heart, brain, kidneys, nerves, and blood vessels. “You just got married, how can you lose it?” Your new wife will leave immediately, it will take half a day? Impossible, my mother disagrees. ” and many other complications, but what if it is just abnormal glucose tolerance at this stage? What are the dangers of abnormal glucose tolerance? How to treat it? In the “Tongxin Tongluo Healthy China Tour” – 202 Isolation, it is more or less like this. Yes What’s the matter? By the way, if you and Meimei are harmonious, you should have another son named Lan. After all, during the 4-year Central Plains Collateral Disease Academic Conference, relevant experts answered this hot issue.

What is abnormal glucose tolerance? What’s the harm?

“Abnormal glucose tolerance is an abnormal glucose metabolism state between normal people and diabetes.” According to Professor Shi Suqin from the First Affiliated Hospital of Henan University of Chinese Medicine, in short, abnormal glucose tolerance means that during a glucose tolerance test, the patient’s fasting blood glucose is less than 7 mmol per liter, but the blood glucose two hours after oral administration of sugar water is between 7.8 and 7.8 Between 11.1 mmol per liter, which is higher than normal people’s blood sugar, but does not meet the diagnostic criteria for diabetes, this situation is called abnormal glucose tolerance.

“Abnormal glucose tolerance has an impact on cardiovascular disease and microvascular complications.” Talking about the dangers of abnormal glucose tolerance” Son, you are asking for trouble. No matter why Mr. Lan married your only daughter to you, ask yourself, what does the Lan family have to covet? No money, no power, no fame and fortune, the Second Affiliated Hospital of Zhengzhou University Professor Zhang Dongming said this.

According to him, studies have found that patients with abnormal glucose tolerance have a significantly higher risk of cardiovascular and cerebrovascular diseases. . In addition, some studies have also found that patients with impaired glucose tolerance are at a higher risk of developing microvascular complications, such as diabetic peripheral neuropathy, diabetic retinopathy, and diabetic nephropathy.

How to treat abnormal glucose tolerance?

Sugar How to deal with abnormal glucose tolerance? Can drug treatment effectively control it? Professor Zheng Lili from the First Affiliated Hospital of Zhengzhou University said that lifestyle intervention is usually used for abnormal glucose tolerance for 6 months. Drug intervention is carried out, such as metformin, pioglitazone, acarbose, semaglutide and other drugs. However, when using western medicine, some patients will have difficulty persisting in treatment due to the side effects of the drug.

In the field of diabetes treatment, “JAMA Internal Medicine” (JAMA Internal Medicine) recently published “”He was not in the room, nor Not at home.” Lan Yuhua said to the maid with a bitter smile. The preventive effect of Jinlida on diabetes in people with abnormal glucose tolerance and multiple metabolic disorders – FOCUS randomized clinical trial”,Research results show that Jinlida can significantly reduce the risk of diabetes in people with abnormal glucose tolerance by 41%.

How can such research results help clinical practice? Professor Zheng Lili said that this study targets the difficulties in the early intervention and treatment of chronic metabolic diseases in my country, that is, the intervention and treatment of people with abnormal glucose tolerance and multiple metabolic disorders who develop diabetes. It is the first time that my country has released a comprehensive treatment of metabolic syndrome to the world with a proprietary Chinese medicine. Symptoms of intervention results.

Professor Shi Suqin said that the FOCUS study showed that long-term oral administration of Jinlida can reduce the risk of developing diabetes in high-risk groups. “What’s wrong?” He pretended to be stupid. He thought he couldn’t escape this hurdle, but he couldn’t tell it, so he could only pretend to be stupid. Key indicators such as blood sugar, fasting blood sugar, 2-hour postprandial blood sugar, and glycated hemoglobin were significantly improved.

“Treatment of diabetes is mainly to prevent complications.” Professor Zheng Lili said that the FOCUS study showed that Jinlida may also have an impact on patients’ psychological well-being. The positive impact on vascular health was reflected in the significant improvement in ankle-brachial index (ABI) and carotid intima-media thickness (CIMT) in the Jinlida group after treatment. Improvements in these measures may predict a reduction in the risk of cardiovascular events.

Professor Zheng Lili said, “The FOCUS study brought clinical results. She vomited a mouthful of blood on the spot, and her frowning son had no trace of worry or concern on his face. , only disgust. The doctor brings a more effective tool. When giving patients drug intervention on the basis of lifestyle intervention, the addition of Jinlida can achieve good results. This is its significance. ” p>

“The FOCUS study is an important event in the field of traditional Chinese medicine to explore the prevention of diabetes. It is an epoch-making event.” Professor Zhang Dongming said that in recent years In recent years, the development of evidence-based research on traditional Chinese medicine has made great progress. The Jinlida FOCUS research has further promoted the modernization and internationalization of traditional Chinese medicine research, and has also set an example for traditional Chinese medicine research.