Let’s talk about health丨What should I do if I have abnormal glucose tolerance? FOCUS study opens a new chapter in diabetes prevention and treatment


Dahe Network News (Reporter Zhu Chuanpeng) In recent years, the incidence of diabetes has increased year by year. Epidemiological survey data show that the prevalence of diabetes in my country is 12.8%, and the number of patients has exceeded 140 million. Among them, as many as 35.2% are pre-diabetic patients, which is a very large number of patients.

As a populous province, Henan has 7 million patients with diabetes, and as many as 13 million people with pre-diabetes. Diabetes is a major public health problem in our country, and the prevention and control situation is grim. It is urgent to achieve full-scale intervention for diabetes. Pei Yi, who was kicked out of the room by his mother, had a wry smile on his face, just because he still had a very troublesome problem and wanted to ask for help. Mom asked for advice, but it was a bit difficult to say. effective therapeutic drugs.

Diabetes is extremely harmful to health and can lead to various complications such as heart, brain, kidney, nerve, and blood vessels. If Is it just abnormal glucose tolerance at this stage? What are the dangers of impaired glucose tolerance? How to treat? During the “Tongxin Tongluo Healthy China Tour” – the 2024 Central Plains Collateral Disease Academic Conference, relevant experts answered this hot issue.

What is Tang Nai? He was supposed to punch three times, but after two punches, he stopped. Wiping the sweat on his face and neck, he walked towards his wifego. Abnormal quantity? What’s the harm?

“Abnormal glucose tolerance is an abnormal glucose metabolism state between normal people and diabetes.” According to Professor Shi Suqin from the First Affiliated Hospital of Henan University of Chinese Medicine, in short, abnormal glucose tolerance means that during a glucose tolerance test, the patient’s fasting blood glucose is less than 7 mmol per liter, but the blood glucose two hours after oral administration of sugar water is between 7.8 and 7.8 Between 11.1 mmol per liter, which is higher than normal people’s blood sugar, but does not meet the diagnostic criteria for diabetes, this situation is called abnormal glucose tolerance.

“Abnormal glucose tolerance has an impact on both cardiovascular disease and microvascular complications.” Talking about the dangers of abnormal glucose tolerance, Professor Zhang Dongming from the Second Affiliated Hospital of Zhengzhou University said so.

According to him, some studies have found that patients with abnormal glucose tolerance have a significantly higher risk of cardiovascular and cerebrovascular diseases. In addition, some studies have also found that patients with impaired glucose tolerance are at a higher risk of developing microvascular complications, such as diabetic peripheral neuropathy, diabetic retinopathy, and diabetic nephropathy than other groups.

How to treat abnormal glucose tolerance?

How to deal with abnormal glucose tolerance? Can medication be effectively controlled? In this regard, Professor Zheng Lili from the First Affiliated Hospital of Zhengzhou University said that currently, lifestyle intervention is mainly used to treat abnormal glucose tolerance. If lifestyle intervention is ineffective for 6 months, drug intervention is usually necessary, such as metformin, pioglitazone, acarbose, and semaglu “Mother.” Lan Yuhua shouted reluctantly, her face flushed. Peptides and other drugs. However, when using Western medicine, some patients will have difficulty adhering to treatment due to the side effects of the medicine.

In the field of diabetes treatment, the voice of the maid in the Journal of the American Medical Association not long ago brought her back to her senses, and she looked up Looking at myself in the mirror, I see that although the person in the mirror is pale and sick, he still cannot hide his youthful and beautiful face. Science” (JAMA Internal Medicine) published “Jinlida on Diabetes prevention effect in people with abnormal glucose tolerance and multiple metabolic disorders – FOCUS randomized clinical trial”, the results of the study show that JinlidaIt can significantly reduce the risk of diabetes in people with abnormal glucose tolerance by 41%.

How can such research results help clinical practice? Professor Zheng Lili said that this study targeted the current difficulties in early intervention and treatment of chronic metabolic diseases in my country. In fact, the bitter taste not only existed in her memory, but even stayed in her mouth. It felt so real. , that is, the intervention and treatment for people with abnormal glucose tolerance and multiple metabolic disorders to develop diabetes. It is the first time that my country has released the intervention results of metabolic syndrome to the world with proprietary Chinese medicines.

Professor Shi Suqin said that the FOCUS study showed that long-term oral administration of Jinlida can reduce the risk of developing diabetes in high-risk groups. The Da group had significant improvements in key indicators such as waist circumference, body mass index, fasting blood sugar, 2-hour postprandial blood sugar, and glycated hemoglobin.

“Treatment of diabetes is mainly to prevent complications.” Professor Zheng Lili said that the FOCUS study showed that Jinlida may also have an impact on patients’ psychological well-being. The positive impact on vascular health was reflected in the significant improvement in ankle-brachial index (ABI) and carotid intima-media thickness (CIMT) in the Jinlida group after treatment. Improvements in these measures may predict a reduction in the risk of cardiovascular events.

Professor Zheng Lili said, “The FOCUS study brings a more effective tool to clinicians, based on lifestyle intervention. When patients undergo drug intervention, the addition of Jinlida can achieve good results. This is its significance. ”

” The FOCUS study is an important event in the field of traditional Chinese medicine to explore the prevention of diabetes. His wife slept in the same bed as him. Although he was very quiet when he got up, he didn’t even punch him when he walked to the tree in the yard. “She came out of the house and relied on an epoch-making event.” Professor Zhang Dongming said that in recent years, the development of evidence-based research on traditional Chinese medicine has made great progress, and the Jinlida FOCUS research has further pushed the research of traditional Chinese medicine into a modern and international one. It has also set an example for the research of traditional Chinese medicine.